Piracetam is stand alone drug which has nootropic properties and it has very good safety profile. Even after thousands of studies, Mechanism of action of piracetam is still matter of debate. Different studies has shown different mechanism of action of Piracetam. Some of those mechanism are as follows.
1. Piracetam is believed to enhance uptake of choline thus increasing synthesis of Acetylcholine and enhancing cholinergic neurotransmitter.
2. Piracetam is reported to have neither stimulant nor depressant action on CNS. It is believed to stimulated ion channels which is responsible for action potential across CNS neurons.
3. Piracetam is reported to have action on AMPA type glutamate receptors where it acts as positive allosteric modulator.
4. Piracetam has been shown to increase density of NMDA type glutamate receptors in CNS which are crucial for memory consolidation and long term potentiation.
5. Piracetam has been shown to increase GABA levels in brain.
6. Piracetam is reported to increase communication between two hemisphere of brain which is crucial for creativity.
7. Piracetam has been shown to increase ATP synthesis and oxygen consumption in brain. Thus, increasing brain activity.
1. Piracetam is believed to enhance uptake of choline thus increasing synthesis of Acetylcholine and enhancing cholinergic neurotransmitter.
2. Piracetam is reported to have neither stimulant nor depressant action on CNS. It is believed to stimulated ion channels which is responsible for action potential across CNS neurons.
3. Piracetam is reported to have action on AMPA type glutamate receptors where it acts as positive allosteric modulator.
4. Piracetam has been shown to increase density of NMDA type glutamate receptors in CNS which are crucial for memory consolidation and long term potentiation.
5. Piracetam has been shown to increase GABA levels in brain.
6. Piracetam is reported to increase communication between two hemisphere of brain which is crucial for creativity.
7. Piracetam has been shown to increase ATP synthesis and oxygen consumption in brain. Thus, increasing brain activity.
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